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Book
P53 : a guardian of the genome and beyond
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Year: 2022 Publisher: London : IntechOpen,

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Abstract

P53 is a protein that plays an important role in the regulation of cell division and thereby offers protection to the cell against malignant transformation. This is the most well-studied and most appreciated role of p53, due to which the protein is famously known as the "guardian of the genome." It is the most studied protein in all forms of cancer research, with much of this research investigating p53's role in tumor suppression. However, research has also shown that p53 plays a role in a wide range of other cellular functions, like serving as a biomarker for environmental pollution. Even as a tumor suppressor and transcription factor, many aspects of p53 function are still obscure, and research in the field is continually attempting to shed light on these functions. This book examines and discusses the myriad roles of p53 and different aspects of its functions. Chapters examine p53 in cancer prevention, DNA repair, gene regulation, and more.


Book
The decision trap : genetic education and its social consequences
Authors: --- ---
ISBN: 1845408314 1845408306 9781845408312 9781845408305 9781845407766 1845407768 Year: 2015 Publisher: Exeter, England : La Vergne, Tennessee : Imprint Academic, Ingram Book Company,

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The Decision Trap questions a dogma of our time: the assumption that genetic education empowers citizens and increases their autonomy. It argues that professional instructions about genes, genetic risks, and genetic test options convey a genetic worldview which destroys self-confidence and makes clients dependent on genetic experts and technologies. Part one of the book introduces the reader to the idea of genetic education. It clarifies the notion of the ""gene"" as it is commonly understood,...

Psychosocial genetic counseling
Author:
ISBN: 1280759933 9786610759934 0199747741 9780199747740 9781280759932 9780195120660 0195120663 0197708447 Year: 2023 Publisher: New York : Oxford University Press,

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Book
Chromosome abnormalities and genetic counseling
Authors: --- ---
ISBN: 0199975175 1283427060 9786613427069 0199749159 9780199749157 9781283427067 9780199975174 6613427063 9780195375336 0195375335 Year: 2012 Publisher: Oxford : Oxford University Press,

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Chromosome abnormalities have been known for over 50 years, though the methods of analysis have become increasing more sophisticated and precise. Surprisingly, the questions that parents and families raise in genetic counseling have changed little over that period. Questions like, ""Why did an abnormality happen? Why did it cause the problems we see in our child? Would it happen again in a future child? How could we avoid it happening again?"" are common concerns for families. This new edition of Chromosome Abnormalities and Genetic Counseling deals with these universal questions, and in the c


Book
Ethical dilemmas in genetics and genetic counseling : principles through case scenarios
Author:
ISBN: 0190206640 0190206659 0190206632 9780190206635 1322075638 9781322075631 9780199944897 019994489X 9780190236359 0190236353 Year: 2015 Publisher: Oxford, [England] : Oxford University Press,

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'Ethical Dilemmas in Genetic Counseling: Principles through Case Scenarios' is essential reading for anyone interested in the ethical issues surfacing in common genetics practice. Written entirely by genetic counsellors, it makes a significant contribution to the field of ethics in genetics and thus will appeal not only to genetic counsellors but to physicians, nurses, and all those concerned with bioethics and social science.

Genetic counselling
Author:
ISBN: 1134890583 1283707896 1282319922 9786612319921 0203019393 9780203019399 9780415082587 0415082587 0415082587 0415082577 9781134890583 9781134890538 1134890532 9781134890576 1134890575 9780415082570 0415082579 Year: 1994 Publisher: London New York Routledge

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Contributions to this study are drawn both from health professionals engaged in genetic counselling and from observers and critics with backgrounds in law, philosophy, biology, and the social sciences. This diversity will enable health professonials to examine their activities with a fresh eye, and will help the observer-critic to understand the ethical problems that arise in genetic counselling practice, rather than in imaginary encounters. Most examinations of the ethical issues raised by genetics are concerned in a broad sense with the application of new technology to human reproduction.


Book
Genetic dilemmas : reproductive technology, parental choices, and children's futures
Author:
ISBN: 1282543695 9786612543692 0199705682 9780199705689 9780195374384 019537438X 0197706819 Year: 2023 Publisher: Oxford : Oxford University Press,

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What limits the genetic choices parents make for their children? Is it okay to select the sex of our children, or for deaf parents to select deaf children? In this second edition Davis argues that parental reproductive autonomy should be limited by respect for the future autonomy of the children created by these measures.


Book
Getting the message across : communication with diverse populations in clinical genetics
Authors: ---
ISBN: 0199977372 9780199977376 1299940331 9781299940338 9780199757411 0199757410 Year: 2013 Publisher: Oxford : Oxford University Press,

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Communicating with patients about genetic concepts is fraught with complications. In addition to the hazy takeaway messages and the likelihood of peripheral findings, the diverse cultural backgrounds of patients in a genetics clinic present another layer of challenge for clinicians and genetic counselors in their aim to communicate important findings effectively and respectfully. This book provides practical advice to assist genetic counselors, geneticists, and other health professionals wanting to engage appropriately with different clients from different communities -- patients who are heari

The hour of eugenics
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ISBN: 1501702254 1501702262 9781501702266 0801425697 9780801425691 0801497957 9780801497957 Year: 1996 Publisher: Ithaca Cornell University Press

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Eugenics was a term coined in 1883 to name the scientific and social theory which advocated "race improvement" through selective human breeding. In Europe and the United States the eugenics movement found many supporters before it was finally discredited by its association with the racist ideology of Nazi Germany. Examining for the first time how eugenics was taken up by scientists and social reformers in Latin America, Nancy Leys Stepan compares the eugenics movements in Mexico, Brazil, and Argentina with the more familiar cases of Britain, the United States, and Germany.In this highly original account, Stepan sheds new light on the role of science in reformulating issues of race, gender, reproduction, and public health in an era when the focus on national identity was particularly intense. Drawing upon a rich body of evidence concerning the technical publications and professional meetings of Latin American eugenicists, she examines how they adapted eugenic principles to local contexts between the world wars. Stepan shows that Latin American eugenicists diverged considerably from their counterparts in Europe and the United States in their ideological approach and their interpretations of key texts concerning heredity.

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